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Collage As social commentary Modern art Photographic process Create a collage that addresses, protests, reacts against, or supports a political, social, or personal cause or idea. 50 points Name: Use the techniques the members of the Dada movement, the Surrealists, or the Constructivists used in order to create a visual impact. Which have you used? Write next to it how it is used. __juxtaposition __use of text __layering __energetic __dream inspired __odd associations __geometric __repetition What is your collage about? Is it more like the Dadaists, Surrealists, or Constructivists? Why? Collage as photographic negative - 50 points Next, you will use your collage to make a contact print in photo paper. On the back discuss how the process of making a collage from color images and then making a photogram of your collage is similar to the photographing we will be doing in this class. Support your opinion!

Next, you will use your collage to make a contact print in photo paper. On the back discusshow the process of making a collage from color images and then making a photogram of yourcollage is similar to the photographing we will be doing in this class. Support your opinion!

Senza titolo-1 · Collage Landscape / 2 . Collage Landscape / 3 . Collage Landscape / 4 . Collage Landscape / 5 . Collage Landscape / 6 . Collage Landscape / 7 . Collage Landscape Documents

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ART 1030A Grading Rubric Rubrics.pdf · poster or digital collage All required content topics are addressed in the poster as well as additional information. All required content topics Documents

Term 4 - Mrs. Udinkmrsudink.weebly.com/uploads/8/1/4/8/81486720/dvc_term_4_web16.pdf · •Use a color scheme ... Rubric: #18 Brainstorm web about your collage project ... #19 Color Documents

Mrs. VanCamp’s AR Book Test Alternative Assignments · If you choose assignment number 3, you cannot do that assignment for another book. You can only ... Rubric 1: Book Collage Documents

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Bachelor of Arts in Christian Ministry Curriculum Map ... · Course ID Course Name Rubric Mini-Justification Rubric Mini-Justification Rubric Mini-Justification Rubric Mini-Justification Documents

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Collage Leño - Azulejos Plaza · collage leÑo gris/musgo 60x60 collage leÑo blanco 60x60 (mo-dular) pg-co2960-4 collage leÑo grafito 29, 8x60. pg-co6060-5 collage leÑo musgo 60x60 DocumentsPlease note that the Web Space Terms of Use have been updated in November 2022 in order to offer a cybersecure service and to better meet the current needs of the network concerning hosting and sharing of pedagogical resources. Any requests for new sites are subject to the new terms of use as of now. For existing sites, the eligibility terms of the free-of-charge Space Web service will become effective as of January 1, 2023.

Do you remember marking final evaluations last session? Did you say to yourself, “Never again”? Never again will I give that assignment because it is too long to grade. Do you spend time going over the copies you have just graded because the last copy you read made you realise that there were criteria that you had forgotten to take into account?

General rubrics should be written with descriptive language, as opposed to evaluative language (e.g., excellent, poor) because descriptive language helps students envision where they are in their learning and where they should go next. Another important way to characterize rubrics is whether they are analytic or holistic. Analytic rubrics consider criteria one at a time, which means they are better for feedback to students (Arter and McTighe, 2001; Arter and Chappuis, 2006; Brookhart, 2013; Brookhart and Nitko, 2019). Holistic criteria consider all the criteria simultaneously, requiring only one decision on one scale. This means they are better for grading, for times when students will not need to use feedback, because making only one decision is quicker and less cognitively demanding than making several. Susan M. Brookhart Using digital rubric generators

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Rubrics disseminated via technology can facilitate more real-time insights for your students. Here are some ideas and tools that you can use to create your own rubrics:

Their homepage touts iRubricas a rubric development, assessment, and sharing tool. It is free to individual faculty and students. You can even send students a copy of the scored rubric securely... no more paperwork, no more calculations.A rubric can be built from scratch or from existing rubrics.

RubiStaris a free online rubric maker to help the teacher who wants to use rubrics but does not have the time to develop them from scratch. It can help you create rubrics for your project-based learning activities. Customizable rubric templates are offered on a variety of topics such as: oral projects, multimedia, math, work skills, science and art. Spanish teachers can use the Spanish version to develop their rubrics.

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In RubiStar, when you use the drop down menu for template categories, the various point value placements will be auto-filled with the appropriate student performance standard that can be modified.

Contrary to the 2 previous rubric generators, Quick Rubric offers a blank template that you can tailor to your weighting system, the number of descriptors that you need and the language that you prefer. You can save rubrics to your free account. They also provide Tips to writing a strong rubric.

Get rid of your paper evaluation grids and create a rubric in Moodle. One of its best features is that when students click on an assignment, which has a rubric attached to it, they will see the rubric as part of the information about their assignment. For a step-by-step guide on how to use rubrics in Moodle, you can consult this documentation or this video tutorial.

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Teams of faculty and other educational professionals from over 100 higher education institutions developed 16 rubrics from the most frequently identified characteristics or criteria of learning for several common higher education learning outcomes. Drafts of each rubric were then tested by faculty with their own students’ work on over 100 college campuses.

You can download and use the 16 rubrics (free, but you must sign in) based on learning outcomes such as critical thinking, oral or written communication, creative thinking, ethical reasoning and teamwork the rubrics, or use them for inspiration in creating your own.

Finally, it is important to note that after the first use of your rubric, you will have to evaluate it and most probably revise it as needed.

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If rubrics are clear and properly aligned to the course’s learning outcomes they will clearly communicate the expectations for an assignment. Not only will you be able to evaluate more efficiently and effectively but also the students will be able to use rubrics to understand what makes a good assignment “good” and a poor assignment “poor”.

Susan MacNeil She has had a busy career in education. With a M.Ed she taught all levels from kindergarten to university. However, most of her career was spent at the college level teaching ESL. She gave Performa courses, lead workshops at SPEAQ, RASCALS and l’AQPC. She served at the

Award. Having retired from teaching she became a contributor to Real Life Stories of education technology integration at . Chinese ink painting helps her relax and travel keeps her energized.

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zornes23253 April 27, 2023 Comment

For professional IT developers it is standard practice to use add-on tools to simplify the development process. The integrated tools of the Professional Developer Edition offer powerful functions to help programmers increase the efficiency and quality of industrial applications.

The Professional Developer Edition is a software suite consisting of add-on tools to optimize the development process. It includes connections to the source code management systems Apache

Editors, as well as tools for test automation and tools for the measurement of execution times (profiling). The software is based on well-known and established standards from the C/C++ world. All tools can be used individually and are fully integrated in .

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The Professional Developer Edition is available as a subscription bundle. With only one subscription and one download, users receive a license for all five tools included in the package.

Integrating UML (Unified Modeling Language™) directly into the development environment: The next logical step after the successful introduction of object orientation in and the IEC 61131-3.

As a user you want to commission high-quality, well-tested IEC 61131-3 applications. The required tests needed to fulfill these requirements can be automated with the Test Manager, an integrated add-on tool for the Development System. The webinar will focus on the following topics:

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From 3.5 the tools of the Professional Developer Edition are available for all platforms. They can be obtained in the Store as a complete bundle, but can also be used individually. The bundle subscription makes it easy to get started: One subscription, one license, one download, and all five bundle tools are immediately at your disposal! A demo version of the tool bundle is also available in the Store.

In addition to single-user licensing, the Professional Developer Edition can be purchased as a bundle of network licenses in the Store.

The Professional Developer Edition subscription is valid for one year. Subscribers receive a notification before the end of the usage period. If the subscription is not cancelled, it is automatically renewed for another year. Licensing is done with a Security Key (not included in delivery) or a software container directly on the PC.

Breaking Down The Stereotype Of A “starving Artist”

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“I think it's just going to be seen as the digital art revolution. I truly believe this is the start of the next chapter in art history.”

At the age of 26, Wisconsin web designer Michael Winkelmann began creating a new piece of digital art in his personal time every single day. He calls them ‘Everydays’.

“I saw a pretty big step-up in the work that I do, ” he says. “The ‘Everydays’ are basically just the pictures that I do every single day, and I’ve been doing those for over 5, 000 days now.”

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Thirteen years later Beeple, as he’s better known, has been commissioned by huge acts like Justin Bieber and Imagine Dragons and he emerged in 2020 as a trail blazing figure in the NFT community. His digital art collections have fetched record prices in the millions at NFT auction houses including Rarible and Nifty and he’s about to take a major step into the mainstream, with Christies offering a collage of 5000 Everydays pieces at auction from Feb. 25 until Mar. 11.

“This monumental digital collage marks the first time Beeple’s work will be sold at a major auction house, ” Christies said in an announcement. “It’s also the first-ever purely digital artwork (NFT) to be offered at a traditional auction house, with its authenticity assured thanks to blockchain technology, ”

Beeple’s work touches on politics and pop culture, with a typical example being a recent image depicting Amazon’s Jeff Bezos as an octopus that he created on the day that the billionaire announced his upcoming retirement as CEO. Winkelmann says his daily ritual has made him a better artist.

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The broader message with this entire Everyday project is just about practicing and looking at things long term. I look at it as one long-term project. And so, incrementally improving and just sticking with something.

Winkelmann, 39, only discovered NFT’s around four months ago, and immediately set to work converting his freely available Instagram art into highly sought after digital collectibles. In November he sold an election-themed digital collectible for $66, 666.60, and a December auction brought in $3.5 million dollars. While one piece went for as much as $777, 777, he also sold hundreds of images for $969 each of which have since gained in value exponentially.

NFT stands for Non-Fungible Token, which means each token is unique and thus distinct from other tokens. Unique tokens make it possible to designate them as representing ownership of specific digital goods, allowing for transferable ownership of digital images, texts, or even in-game items.

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I think it’s just going to be seen as the digital art revolution. I truly believe this is the start of the next chapter in art history.

The Wisconsin artist says that while everything is reproducible on the internet, NFTs allow for individual ownership of a piece even though it is copied and circulated widely.

“I’m very open with allowing people to share stuff and post it wherever, ” he says. “You can’t police the f—ing Internet. You post on the Internet, it’s the f—ing Internet! The cool thing about the blockchain is that you can kind of have it both ways.”

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He adds that NFT’s are a “very advantageous way of collecting art, because it will live on as long as the blockchain lives on, and it can take all different forms.”

Got 4 offers today in the $12-$14k for @beeple's Politics is BS NFT. What is going on ? I bought it for $1k like 2 months ago. pic.twitter.com/q94wXmi3xh — ? Matty (@DCLBlogger) February 8, 2021

Last December, Winkelmann hit the crypto news headlines after he auctioned off a collection of digital artworks for $3.5 million on the Nifty platform. While the previous 13 years of Everydays accompanied a steady career progression of better clients and ever-increasing paychecks, he wasn’t quite prepared for “overnight” success.

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“That was the big shift where it was like ‘oh shit this is it’, this is a crazy opportunity to look at my work that I never really thought about as being collectible, and now suddenly it’s like ‘wow this is very collectible!’”

But he points out he wasn’t a starving artist before the auction: “[Many people] think this is a little bit more rags to riches than it is. I was making pretty good money before.”

While he credits his success to a large social media following and established name as “one of the most well known digital artists, ” Winkelmann acknowledges that he was also in the right place at the right time with little competition.

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There’s a lot of low hanging fruit […] In more mature spaces, you really need to come up with a fantastic idea to stand out, everybody has already got the easy shit. It feels like there’s still a lot of easy shit to try.

It is said that art is either plagiarism or revolution. The art world is in a constant state of redefinition, and it’s normal for new styles to begin as underground ‘degenerate’ movements that struggle for acceptance in the established art world. In this way it’s similar to cryptocurrency, which was first dismissed and derided by traditional investors and institutions, many of whom are now re-evaluating.

In the past, Winkelmann says that neither graphic art, nor graphic artists, could really exist in the traditional sense. No graphic artist could truly sell their personal work — they had to work as artisans because working as an independent digital artist was not an option.

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“It wasn’t. There was just no way to collect your work. The technology did not exist, and the market did not exist… Everybody was just, you know, freelance, or they just had a job or whatever.”

This means that the innovation of NFT’s representing ownership of digital art represents a pivotal moment in art itself: art no longer needs be a physical item to be sold and displayed, but is equally legitimate as a digitally expressed and cryptographically transferrable manifestation of the artist’s mind.

Winkelmann said the upcoming Christies auction of his collage will be another milestone, as its a major auction house conducting “their first ever 100% digital auction. There will be no physical piece; they’re literally just auctioning off a JPEG. And so, I think that will be a very big moment, and big validation for this space. They’ll also be accepting Ether for this auction for the first time ever.” (Christies auctioned a combination physical work/NFT piece last year for $130, 000.)

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“Whoever buys it, I will work with them in the future to be like ‘okay, so how do we want to show this?’ Do we want to project it on the side of a building, do we want to make a giant canvas of it? Do we want to put it on a big screen? The artwork itself can take a bunch of different forms; that’s the beauty of digital art.”

Christie's is proud to offer "Everydays – The First 5000 Days" by @beeple as the first purely digital work of art ever offered by a major auction house. Bidding will be open from Feb 25-Mar 11. Learn more here https://t.co/srx95HCE0o | NFT issued in partnership w/ @makersplaceco pic.twitter.com/zymq2DSjy7 — Christie's (@ChristiesInc) February 16, 2021

Beeple’s NFT journey from avant-garde to acceptance follows an arc not dissimilar to other hugely successful artists like Banksy, whose graffiti stencil art reliably sells for millions today. “20 years ago that wasn’t the case. That was vandalism. Like graffiti is not, you know, ‘art’, it’s vandalism.”

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Indeed, we need not go far back in time to find similar narratives within the blockchain space. Back in early 2018 Cryptokitties, one of the first NFT projects, was slowing down the entire Ethereum network causing people to accuse the lovable but useless NFT cats of ruining Ethereum.

It is an unfortunate arc d’art that experimental artists are often under-appreciated in their time, with the likes of Van Gogh and Monet dying in obscurity before achieving wide recognition for their work. “So are you saying I’m going to die?” Winkelmann asks sarcastically but with a hint of existential dread, to which I reassure him that he appears well ahead of his historical peers. He agrees. “I feel very lucky to be in this position, especially so young to be able to capitalize on this.”

“Honestly, I’m really just putting it back in, making more and more art and cooler projects that I didn’t have the ability to do […] anybody who is collecting my artwork, I very much look at them as ambassadors, and they’ve sort of given me that money to like ‘OK there you go, go do even cooler things’, and that’s what I want to do. I want to do bigger projects, that obviously requires more money, or hiring people, or this or that.”

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Considering his generous art budget, I suggest an NFT Bitcoin Lamborghini that comes with a real, physical lambo as a bonus physical token. “I think that’s a good idea, that would be great! Is it a green or a yellow lambo?” he asks. “I’ve got to figure out something like that, I feel like that would be very interesting.”

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zornes23253 April 21, 2023 Comment

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All articles published by are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by , including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https:///openaccess.

Feature papers represent the most advanced research with significant potential for high impact in the field. A Feature Paper should be a substantial original Article that involves several techniques or approaches, provides an outlook for future research directions and describes possible research applications.

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Editor’s Choice articles are based on recommendations by the scientific editors of journals from around the world. Editors select a small number of articles recently published in the journal that they believe will be particularly interesting to readers, or important in the respective research area. The aim is to provide a snapshot of some of the most exciting work published in the various research areas of the journal.

By Milena Rmandić 1 , Ana Stajić 2 , Jasna Jančić 3 , Janko Samardžić 3, 4 , Nebojša Jović 3, † and Anđelija Malenović 1, *

In this research, a UHPLC–MS/MS method was developed and validated for the determination of zonisamide in dried plasma spots (DPS) and dried blood spots (DBS). Detection of zonisamide and internal standard, 1-(2, 3-dichlorphenyl)piperazine, was carried out in ESI+ mode by monitoring two MRM transitions per analyte. Total run time, less than 2.5 min, was achieved using Acquity UPLC BEH Amide (2.1 × 100 mm, 1.7 µm particle size) column with mobile phase comprising acetonitrile–water (85:15%, v/v) with 0.075% formic acid. The flow rate was 0.225 mL/min, the column temperature was 30 °C and the injection volume was 3 µL. Desolvation temperature, desolvation gas flow rate, ion source temperature and cone gas flow rate were set by the IntelliStart software tool in combination with tuning. All of the Guthrie cards were scanned, and DPS/DBS areas were determined by the image processing tool. The influence of hematocrit values (20–60%) on accuracy and precision was evaluated to determine the range within which method for DBSs is free from Hct or dependency is within acceptable limits. The validated method was applied to the determination of zonisamide levels in DPS and DBS samples obtained from patients confirming its suitability for clinical application. Finally, the distribution of zonisamide into the red blood cells was estimated by correlating its DPS and DBS levels.

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Zonisamide (1, 2-benzisoxazole-3-methanesulfonamide) is an antiepileptic drug (AED) chemically distinct from other AEDs, with a dual mechanism of action, and thus effective in patients whose seizures are resistant to other anticonvulsants. Its biotransformation products are neither active nor toxic since 20% of zonisamide undergoes acetylation to form N-acetyl zonisamide, and 50% is reduced to form the open ring metabolite 2-sulfamoylacetyl phenol (SMAP), which is eliminated as glucuronide, while 30% is excreted unchanged in the urine [1]. The drug is not highly bound to human plasma proteins, but its binding affinity for red blood cells (RBCs) is eight times higher than that for plasma proteins, and a marked concentration of zonisamide can be observed in human RBCs [2].

For the determination of zonisamide (ZNS) in plasma/serum HPLC [3, 4], LC-MS [5], LC-MS/MS [6, 7] and UHPLC–MS/MS [8] methods were reported, while in dried plasma spots (DPSs) it was quantified by HPLC-UV method [9]. The reported HPLC methods suffer from incorrect validation procedures and inadequate lower limit of quantification (LLOQ), while LC-MS methods encountered several disadvantages such as a lack of specificity due to the application of selected ion monitoring (SIM) rather than multiple reaction monitoring (MRM) modes [5], inadequate LLOQ [6], laborious sample preparation procedures [5, 7] or compromised cost-effectiveness due to long analytical run [7]. UHPLC–MS/MS dramatically improved analytical run times without sacrificing peak resolution, but its clinical application is limited only to serum after protein precipitation for sample pre-treatment [8].

Thus far, a method suitable for quantification of ZNS in both plasma and blood was not proposed, providing means to correlate obtained concentrations and apply findings in routine clinical practice. Therefore, the aim of this research was to develop the first UPLC–MS/MS method for the quantification of ZNS in DPSs and dried blood spots (DBSs) with the aid of image processing for precise estimation of DBS and DPS areas after scanning of the Guthrie card on which the appropriate matrix volume was spotted. For the appropriate collection of DBSs, regardless of hematocrit (Hct) value, we applied a previously verified procedure for consistent application of a blood sample volume and formation of spots of the uniform area [10].

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Furthermore, both methods were validated in accordance with Food and Drug Administration (FDA) [11], European Medicines Agency (EMA) [12] and International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) M10 guidelines [13] on bioanalytical method validation, as well as European Bioanalysis Forum (EBF) recommendations on DBS assays [14]. The DBS-based method was validated using 5 Hct levels (20.2%, 30%, 42%, 50.2% and 60%) to determine the range within which the method is independent of Hct or dependency is within acceptable limits. Finally, the suitability of the developed methods for the clinical application was confirmed by analyzing samples obtained from epileptic children and youth.

Reference standard of ZNS, as well as the internal standard, 2, 3-dichlorphenilpiperazine was obtained from LGC standards (LGC Group, Teddington, UK) (Figure 1). Acetonitrile, methanol and water, all LC-MS grade, were purchased from Thermo Fischer Scientific (Massachusetts, USA). Formic acid (purity 99%), acetic acid, ammonium formate and ammonium acetate, also LC-MS grade, were obtained from Sigma Aldrich (Taufkirchen, Germany). Vacutainer K2EDTA tubes for blood collection were supplied by Becton Dickinson, UK.

Air displacement Eppendorf pipette with variable volume 1–5 mL (Eppendorf AG, Hamburg, Germany) was utilized during the preparation of blood samples of target Hct values. Whatman 903 cellulose-based Guthrie cards utilized for DBS and DPS sample collection were procured from GE Healthcare (Buckinghamshire, UK). Thermo automatic pipettes with fix volume of 50 µL, variable volume of 10–100 µL and 0.1–10 µL (Thermo Fischer Scientific, Massachusetts, USA) and non-commercial puncher were used during the sample deposition onto the blotting paper, as well as during analytical sample preparation procedure. Fisherbrand™ Zipper Seal Sample Bags (Fisher Scientific, Hampton, VA, USA) with Sorb-It 1 g desiccant packs (Clariant, Ahrensburg, Germany) were used for card storage. Millipore membrane filters of 0.22 µm pore size and 47 mm diameter were purchased from Sigma Aldrich (Merck KGaA, Darmstadt, Germany). Blank plasma was obtained from Sanquin (Amsterdam, The Netherlands), while blank blood was obtained from healthy volunteers. Plasma and blood samples were collected from patients of the Clinic of Neurology and Psychiatry for Children and Youth in Belgrade, Serbia, who are using ZNS in therapy.

Pdf) Lamotrigine Versus Levetiracetam Or Zonisamide For Focal Epilepsy And Valproate Versus Levetiracetam For Generalised And Unclassified Epilepsy: Two Sanad Ii Non Inferiority Rcts

The chromatographic analysis was performed on the Waters Acquity UPLC H-Class system. Appropriate chromatographic behavior of ZNS and IS for a total run time of less than 2.5 min was achieved using Acquity UPLC BEH Amide (2.1 × 100 mm, 1.7 µm particle size) column and isocratic elution. The mixture of acetonitrile and water (85:15%, v/v), with added formic acid to the final content of 0.075%, was selected as the optimal mobile phase composition. The flow rate was 0.225 mL min

The analysis was conducted on Waters Xevo TQD, a triple quadrupole mass spectrometer armed with an electrospray ion source (ESI). Detection and quantification of the ZNS and IS were carried out in the positive electrospray ionization (ESI+) followed by scanning in multiple reaction monitoring (MRM) mode. Two MRM transitions were used/monitored for each analyte. Waters Xevo TQD’s operating parameters such as desolvation temperature, desolvation gas flow rate, ion source temperature and cone gas flow rate were set at 500 °C, 1000 L h

, respectively, while the optimal value of collision energy (CE), cone voltage (CV) and capillary voltages for each m/z transition was set by IntelliStart software tool in combination with tuning. Characteristic m/z transitions (parent > product ion), as well as CE and CV for each transition, are listed in Table 1.

Lgs Foundation 2016 Conference

EBA 20 Hettich centrifuge (Hettich GmbH & Co. KG, Tuttlingen, Germany) and Mythic 18 hematology analyzer (Orphée Medical, Geneva, Switzerland) were utilized during the preparation of blood samples of target Hct levels. Vortex Genie 2 Digital (Scientific Industries, Inc., Bohemia, NY, USA) was employed during the sample preparation procedure. All DPS and DBS samples were scanned by HP Scanjet 4070 Photosmart Scanner (HP, Palo Alto, CA, USA).

Mass Lynx V4.1 software (Waters Corporation, Milford, MA, USA) provided the execution of all operations at the Waters Acquity UPLC/Xevo TQD systems. The IBM

Office Excel 2013 software packages (Microsoft Corporation, Redmond, Washington, DC, USA) were used to process the results and perform the necessary statistical tests. The image processing tool of Matlab R2018b software (MathWorks, Natick, MA, USA) was employed to determine the accurate plasma and blood spot area. The Greenness Analytical

Drug Repurposing For The Treatment Of Covid‐19: A Knowledge Graph Approach

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zornes23253 April 20, 2023 Comment

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Pdf) Lamotrigine Versus Levetiracetam Or Zonisamide For Focal Epilepsy And Valproate Versus Levetiracetam For Generalised And Unclassified Epilepsy: Two Sanad Ii Non Inferiority Rcts

Lgs Foundation 2016 Conference

Drug Repurposing For The Treatment Of Covid‐19: A Knowledge Graph Approach

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